Sentence examples for suppressive by from inspiring English sources

These miRNAs are either pro-oncogenic, by targeting tumor suppressor genes, or tumor suppressive, by silencing the oncogenes [ 12].

Finally, it should be noted that IDO+ cells may be immune suppressive by other means than by the expression of IDO.

The expression of IL-6 by DCs activated through Toll-like receptors has been shown to make responder T cells refractory to suppression by suppressive T cells [ 52].

This was achieved by eliminating ion suppressive effects by (i) cross-linking carboxyl/amino containing molecules on tissue with 1-ethyl-3-[3- dimethylamino propyl]-carbodiimide hydrochloride and (ii) removing highly abundant phosphatidylcholine head groups via phospholipase C treatment.

As regards cancer, autophagy may play a tumor suppressive role by preserving cellular integrity during tumor development and by possible contribution to cell death.

Induction of autophagy by natural products may contribute to its tumor suppressive effect by causing cell senescence, inducing apoptosis-independent death, and provoking apoptotic death.

The described putative suppressive effect by intracellular collagen retention may at least partly be neutralized by a stimulatory effect via increased SOX9 expression, which is known to function as an enhancer for Col2A1 [ 36].

Among many others, PML has also been established to mediate its tumor suppressive role by mitigating the inactivation of active AKT (pAKT) inside the nucleus by assembling a dephosphorylating platform for nuclear pAKT.

Acidification of the suppressive soils by H2SO4, promoted the infection.

In addition, TLR activation in these cell types opposes the immune suppressive environment by favoring CNS tropism.

MiR-128a demonstrated tumor suppressive effects by potently inhibiting the colony formation of medulloblastoma cells.