Sentence examples for suppressive activities from inspiring English sources
Naturally occurring activated Tregs, ready to exert their suppressive activities, are defined as CD4+CD25hiFoxp3+ T cells [ 16].
Deleted in liver cancer 1 (DLC1), a member of RhoGTPase activating protein (GAP) family, is known to have suppressive activities in tumorigenicity and cancer metastasis.
Alternatively, in parallel with accumulation of VAT-resident Foxp3+ Treg cells, augmentation of such suppressive activities of PPAR γ-expressing Treg cells achieved by ligand activation may enable better control of inflammation in obesity.
RNase L mediates critical cellular functions including antiviral, proapoptotic, antiproliferative and tumor suppressive activities.
As hypermethylation is often observed for silenced tumor suppressor genes (TSGs), hypermethylated biomarker genes might exhibit tumor suppressive activities upon re-expression.
Furthermore, allergic asthmatic BAL could suppress IL-10 production by healthy control pulmonary Treg in a TSLP-dependent manner.These results provide the first evidences for a direct role of TSLP in the regulation of suppressive activities of Treg.
Whereas membrane-bound, full-length CD83 co-stimulates the immune system, a soluble variant (sCD83), consisting of the extracellular domain only, displays strong immune-suppressive activities.
Chimeric proteins with amino acid swaps in this segment show unaltered immune-suppressive activities in a TNF-α assay when compared to wild-type sCD83.
Core, NS3 and NS5A have interferon-suppressive activities detectable through in vitro assays, and hence these activities also appear to function in human patients.
TGF-β1 is a pleiotropic growth factor with both growth-promoting and growth-suppressive activities depending on circumstances, including dose, target cell type and context [11], [22] [23], [39], [45], [48] [50].
TGF-β1 is a pleiotropic growth factor with both growth-promoting and growth-suppressive activities depending on circumstances, including concentration, target cell type and context [13] [15], [26], [34], [42], [45], [46].
