Sentence examples for suppression screen from inspiring English sources

To pursue genetic interactors of ESA1, a dosage suppression screen was performed on an esa1 mutant.

To characterize the molecular mechanism by which Vmem change regulates ITLS phenotypes, we performed a suppression screen.

Thus, we anticipated that a "chemical suppression" screen by using HU would identify mutations in genes that either directly participate in chromosomal DNA replication or its regulation.

These processes can be independently targeted, in a suppression screen (Adams and Levin, 2012a) to identify the specific mechanisms that, when blocked, inhibit the ability of hyperpolarizing channels to reduce ITLS incidence (Fig. 6A).

In order to begin to identify biophysical mechanisms that transduce Vmem changes to downstream events during voltage-mediated suppression of ITLSs, we performed a suppression screen using well-characterized inhibitors of Vmem sensing processes.

We performed a "chemical suppression" screen by using a previously described collection of temperature-sensitive (TS) mutants (Li et al. 2011) and sought those mutants that showed improved growth in the presence of HU at the otherwise-restrictive temperature where the mutant would normally fail to grow.

Furthermore, "chemical suppression" screens have implications in the identification of novel functions and therapeutic potentials of existing chemical compounds.

We suggest that "chemical suppression" screens in yeast provide an efficient and meaningful tool for novel drug function discovery.

Thus, "chemical suppression" screens will help us devise cautionary measures in chemotherapy to avoid administering drugs that can suppress mutations in the cancer genome.

"Chemical suppression" screens were performed with the TS mutant collection (MAT a his3 Δ 1 leu2 Δ 0 met15 Δ 0 ura3 Δ 0 yfg:: yfg ts-KanMX) from Charlie Boone's laboratory at the University of Toronto (Li et al. 2011).

Sparse plates with a majority of small or dead colonies, such as those seen in suppression screens, usually fail to process properly, as there is not enough information to establish the grid.