Sentence examples for suppression pathway from inspiring English sources
The floral time regulators in both the Ehd2-OsMADS50-Ehd1-RFT1 LD andivathen pathway and the OsGI-Hd1-Hd3a LD suppression pathway exhibit diurnal oscillation patterns (Matsubara et al. 2008; Ryu et al. 2009).
The delay flowering effect of Hd6 is observed only when Hd1 is functional, however, Hd1 is not phosphorylated by Hd6 in vitro (Ogiso et al., 2010), suggesting that Hd6 phosphorylates unknown substrates that cooperate with Hd1 in the LD floral suppression pathway.
Validation experiments allowed us to infer a tumor suppression pathway involving miR-181c (Figure8).
From these data sets, we inferred and validated a tumor suppression pathway linked to miR-181c.
HER2/neu has also been shown to disrupt the p53 tumor suppression pathway [ 31].
The PTENP1-PTEN association is involved in various cancers, which indicates a common regulatory activity of the tumor suppression pathway.
The motor decision is modeled as a single variable (hereafter, referred to as the execution process) that is assumed to reflect the differential activity between the direct (facilitation) and indirect (suppression) pathways; that is, as facilitatory systems are recruited more than the suppressive systems, the execution process accumulates toward the decision boundary.
These observations suggested that DDB2 may play a role as a downstream mediator in the tumor suppression pathways of p53 and BRCA1 [18], [18].
It is tempting to speculate that this type of mechanism may act in some spontaneously regressing tumors, such as stage IV-S neuroblastoma, however, such a mechanism would be co-dependent upon other classic tumor suppression pathways, including p53 and p21.
These tumor suppression pathways represent a gauntlet that carcinogen-exposed cells must overcome in order to acquire cancerous properties.
At the meeting, Yaswen presented work on two main tumor suppression pathways involved in blocking indefinite proliferation of breast cells derived from normal human tissue.
