Exact(2)
One mechanism of immune suppression operating in cancer involves immune cell intrinsic checkpoints that are present on the surface of activated T cells.
These results support and reinforce our in vitro data and implicate CD8+ Treg cells within the infected liver as the mediators of suppression operating in an antigen-specific manner.
Similar(58)
These results suggest that MET suppression operates at the level of the ER-associated pool of partially glycosylated VEGFR2 polypeptides.
Thus, similar to its activator p53, lincRNA-p21 may play an important role in tumour suppression by operating as a transcriptional repressor.
If inflammation arises from the absence of a basal suppression of inflammation by wt-CFTR, this loss of suppression may operate alongside the positive pro-inflammation function for mutated CFTR reported by many groups.
United Airlines temporarily grounded 11percentt of its fleet and canceled 31 flights Wednesday while it tested dozens of Boeing 777s to make sure components of a cargo fire suppression system were operating effectively.
The drug business, dependent on a well-established witness-suppression program, operates a far more powerful system of deterrence, with far swifter punishment, than any lawful state could ever devise.
It is possible that some nonsense-suppression mechanism operates in the brain.
In summary, this study shows that HSP70 can modulate inflammation in a model for chronic and progressive arthritis through IL-10 dependent mechanisms, operating via suppression of pathogenic antibody responses and the development of regulatory T cells.
Furthermore, in the presence of an attentionally-demanding RSVP task performed at central fixation, the BOLD responses elicited by large, high-contrast peripheral visual distractors in areas V1 to V4 in one hemisphere were unaffected by the presence of ipsilateral visual distractors, suggesting that 'surround suppression' does not operate inter-hemispherically [22].
In mature pollen, translational suppression may thus operate to inhibit production of protein products from stored transcripts (or transcripts in the process of storage), enabling transcripts to be accumulated during pollen maturation without concomitant protein synthesis.
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