Sentence examples for suppression of trail from inspiring English sources

Expression of Caspase-8 was also not significantly altered in resistant cell lines; this is in contrast with recently published data that identified Caspase-8 expression levels as a biomarker of TRAIL sensitivity in HNSCC, suggesting a potentially different mode of suppression of TRAIL receptor-dependent apoptosis in breast cancer.

The buffer rod tested has tapered shape and cladding on the side wall as a further suppression of trailing echo.

Suppression of TRAIL-R2 cell-surface expression by HCMV could be detected as early as 24 hr after infection, yet it became more marked as the infection progressed through 48 and 72 hr.

As shown in Figure 2b, suppression of TRAIL-mediated ICAM-1 expression by zVAD-fmk was not further affected by addition of NF- κB inhibitors such as SN-50 or lactacystin.

Then there's the suppression of trade unions.

To translate the above findings to TRAIL-based therapy against colon carcinoma metastasis, we next examine the function of TRAIL in suppression of colon carcinoma in preclinical mouse models.

We found here that rotenone was able to increase DR4 and DR5 mRNA transcripts, protein expression and surface expression, furthermore, silencing of DR4 and DR5 expression in A549 cells led to significant suppression of cell apoptosis induced by TRAIL plus rotenone.

Mohr et al. demonstrated that long-term expression of TRAIL mediated by AAV led to a marked suppression of colorectal tumors in mouse with a single intratumoral injection of AAV/TRAIL vector [ 23].

The effect of TRAIL expression on blood lymphocytes was reported to be different (killing versus suppression) than that observed with RA synovial cells.

Genetic suppression of c-FLIP resulted in the partial sensitization of TRAIL-resistant cancer lines to the pro-apoptotic effects of TRAIL, irrespective of their cellular phenotype, yet normal mammary epithelial cells remained refractory to killing.

Lemke, J. et al. Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1.