Exact(13)
Fig. 2 Network of defense-related pathways showing the expression or suppression of key genes belonging to metabolism of secondary metabolites including salicylic acid, jasmonic acid, ethylene, and hormones.
These results indicate that the expression of a soluble protein leads to an enhanced suppression of key metabolic pathways, adversely affecting the cellular health and productivity of the host.
These processes result from polycomb suppression of key developmental pathways, including Wnt and Notch [9] [11].
Recent studies have shown that the ES cell pluripotent state is critically maintained by Polycomb group (PcG) complexes that mediate suppression of key differentiation genes [12] [14].
Our data above show that GRHL2 inhibits keratinocyte differentiation through transcriptional suppression of key target genes.
However, in light of our findings, suppression of key immune responses by Bd is likely an important factor in the lethality of this fungus.
Similar(47)
Suppression of consuming key elements in the electrode materials is essential in this concern.
We examined suppression of a key effector cytokine that is widely reported to be preserved in HIV infection, IFN-gamma [26].
A suppression of a key catalytic gene suggests the iron-inefficient genotype may be energetically challenged to maintain a stable cellular environment.
At face value, this might be interpreted as specific suppression of two key interacting components of a cognate immune response, a well-described mechanism of tumour-induced suppression (Pinzon-Charry et al, 2005b).
Down-regulation of STAT1 is in agreement with the suppression of its key regulators IFN- γ, EGFR and PDGF [ 80], and contributes to activation of inflammation-associated genes IRF-1, iNOS, and TNF- α.
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