Sentence examples for suppression of function from inspiring English sources

In contrast, we did not see a significant association between homozygous mutation of PIK3CA (1/7), CDKN2A (2/6), PTEN (5/12), RB1 (2/9) and CDH1 (2/10) genes and their localized regions, perhaps because, some of these genes (CDH1, CDKN2A, PTEN) undergo suppression of function by hypermethylation (Table S5).

Elevated plasma glucose caused passive 20 30% increases in regional brain glucose levels, which also occurs during anaesthesia and suppression of function and metabolism.

Often, DNA methylation and histone deacetylation of tumour suppressor genes occur in many human cancers, leading to suppression of function of these genes thereby conferring a growth advantage for the tumour cells (Robertson and Jones, 2000; Macaluso and Giordano, 2004).

The transcriptional trends highlighted in this study imply that these cells become biofactories not by gain of function, but by a broad suppression of function to effectively push all of the cell's resources towards a very few important tasks such as the massive synthesis of lipids and of a large quantity of a minority of proteins.

Protein modification by POVPC may lead to activation of apoptotic signaling components, as well as suppression of functions that help the cell survive.

If TLR8 function is inhibited by suppression of lysosomal function, antibiotic treatment efficiently blocks bacteria-driven inflammatory responses in infected human whole blood cultures.

To elaborate the role of suppression of ovarian function in premenopausal patients with endocrine-responsive breast cancer more clearly, three trials were sponsored by the International Breast Cancer Study Group and coordinators.

A critical question is how does suppression of NMDAR function promote protein synthesis to enhance synaptic function?

The authors suggested that PACAP suppressed induction of EAE primarily via suppression of APC function and inflammatory cytokine production.

This could be interpreted as a Ba2+ induced suppression of visual function, although electrophysiological evidence suggests otherwise, at least in terms of outer retinal function.

The improvements to cardiac function with ASA without alteration to cardiac pathology or structure indicated a humoral mediator in the suppression of cardiac function.