This week, I want to discuss something I call "suppression, regression, depression".
Conditions of stress precipitated glucose intolerance, immuno-suppression, behavioural depression, cognitive deficits and male sexual dysfunction in rats.
In support of this, our data reveal strong suppression of depression-like behavior in mice lacking GluN2B specifically in pyramidal cortical neurons.
We show here that genetic deletion of GluN2B from principal cortical neurons both mimics and occludes the effects of ketamine in suppression of depression-like behavior and increased frequency of individual excitatory synaptic events onto layer II/III pyramidal neurons in PFC.
Depression suppression and anxiety suppression had no significant effect on depressive symptoms, though both subscale scores were significantly correlated with CES-D scores.
Although continuous intravenous opioid infusion may be useful and safe for cardiac surgery, it is related to cough suppression and respiratory depression and can prolong duration of intubation, particularly in elderly patients.
Interferons are involved in a wide range of clinically important phenomena, ranging from activation of immune responses to infection [14] to cancer suppression [16] to depression [17].
The other reactions--anger, depression, suppression, denial--took a little piece of me with them.
Some studies support a primary respiratory cause with central apnoea, which has been related to postictal generalized EEG suppression, indicating profound depression of CNS functions (Lhatoo et al., 2010).
This mechanism has been implicated in short-term synaptic depression, including suppression of excitatory or inhibitory transmission (see Lovinger 2008, for review).
