Sentence examples for suppressing translation from inspiring English sources

MiRNAs can play multiple roles, suppressing translation directly or through targeting transcript for degradation through deadenylation or endonucleic cleavage [17].

MicroRNAs are small non-coding RNAs known to regulate the target transcripts by promoting mRNA degradation and suppressing translation [1], [2].

MicroRNAs are small (∼22 nucleotides) non-coding RNAs known to regulate the expression of target genes by promoting mRNA degradation and suppressing translation [1], [2], [3], [4].

MicroRNAs (miRNAs) are a family of endogenous, small and noncoding RNAs that negatively regulate gene expression by suppressing translation or degrading mRNAs.

Therefore, we examined protein stability by suppressing translation using 10 μg/ml cycloheximide (CHX).

miRNAs negatively regulate the expression of target mRNAs by suppressing translation or decreasing the stability of mRNAs [ 4].

In a recent report by Triboulet [ 17], miR-17-5p washownwn to bind to PCAF 3'UTR to suppress translation, resulting in suppression of the PCAF gene at the posttranscriptional level in HeLa cells.

Suppression therapy utilizes compounds that suppress translation termination at in-frame premature termination codons (PTCs) to restore full-length, functional protein.

In the cytoplasm, mRNAs actively translated by polyribosomes are targeted by miRISC complexes to suppress translation [ 54].

Similarly, PERK homodimerization and autophosphorylation induces phosphorylation of the α subunit of translation initiation factor 2 (eIF2α), which blocks formation of ribosomal preinitiation complexes and suppresses translation initiation, thereby attenuating general mRNA translation.

Long repeats in 5'UTR of FMR1 suppressed translation.