These precipitates served as effective sinks for point defects during subsequent elevated-temperature irradiation, suppressing radiation-enhanced diffusion.
These observations are consistent with data showing that 1,25(OH)2D suppressed secretion of IL-8 by interfering with NFκB signaling in RWPE1 cells [ 31] and that it enhanced radiosensitivity of prostate cancer cells by selectively suppressing radiation-mediated RELB activation in prostate cancer cell lines [ 55].
These results suggest that, in the optimal treatment regimen, YC-1 enhanced the therapeutic effect of radiation through (1) suppressing radiation-induced HIF-1 α expression and HIF-1 activity, (2) suppressing HIF-1-dependent secretion of radioprotective protein(s) such as VEGF, (3) increasing radiosensitivity of endothelial cells and (4) decreasing microvessel density.
Instead, we use a passive shielding method to suppress radiation counts.
Here we investigate a receiver design that utilizes aerogels to suppress radiation losses, boosting the efficiency of solar thermal conversion.
The trial functions are then used to analyze the resolution enhancement and signal attenuation produced by pulse sequences that suppress radiation damping.
In a new strategy, we sought to determine whether vasoconstriction and transient hypoxia of the mucosa during irradiation would prevent or suppress radiation-induced oral mucositis.
To determine whether acute administration of mice with IGF1 could suppress radiation-induced salivary gland hypofunction, FVB mice were anesthetized with avertin, injected with 5 µg IGF1, and immediately exposed to 1 Gy radiation.
Expression of activated myr-Akt1, or pretreatment of mice with recombinant IGF1, which activates Akt, significantly decreases the number of apoptotic cells, and significantly suppresses radiation-induced salivary gland dysfunction.
Both bFGF and VEGF suppress radiation-induced ASMase activation, ceramide generation and apoptosis, and restoration of ceramide levels by exogenous addition completely restores apoptosis even in continued presence of VEGF/bFGF.
