Exact(16)
Thrombomodulin (TM) serves as a vasoprotective molecule on the surface of vascular endothelial cells (VECs) to maintain the endothelial microenvironment by suppressing cellular proliferation, adhesion and inflammatory responses.
We have previously identified 7SK snRNA as well as HEXIM1/2, LARP7 and MePCE proteins as key subunits of this complex and determined their roles in inhibiting CDK9 kinase, maintaining 7SK snRNP integrity and suppressing cellular transformation.
SAHA can induce hyperacetylation of the HIV promoter-associated nucleosomes to activate latent HIV by suppressing cellular HDAC expression and binding to the HIV promoter [30 32].
Regulatory B cells that secrete IL-10 (IL-10 Bregs) represent a suppressive subset of the B cell compartment with prominent anti-inflammatory capacity, capable of suppressing cellular and humoral responses to cancer and vaccines.
They are an important component of the treatment of diseases in which inflammatory response plays a central role, suppressing cellular infiltration and increasing the synthesis of lipocortins, mainly [6].
Taken together, our results suggest that GR significantly extends the lifespan of multiple cell lines through suppressing cellular aging processes leading to a prolongation of lifespan in vitro.
Similar(44)
In addition to its anti-angiogenic activity, ELH significantly suppressed cellular metastatic activities, including migration, invasion, and proteolysis, via suppression of p38, JNK and NF-κB activation (Figs 1, 2, 3).
Lung fibroblasts exposed to GSH had substantially suppressed cellular proliferation, whereas oxidized glutathione disulfide (GSSG) had no suppressive effect on proliferation [ 288].
Guilding, C. et al. Suppressed cellular oscillations in after-hours mutant mice are associated with enhanced circadian phase-resetting.
We observed that silencing Linc02527 suppressed cellular proliferate; however, ectopically expressed Linc02527 promoted the cellular proliferate ability in HTR8 cells (Fig. 3g i).
Re-introduction of α-catenin into HL-60 myeloid leukemic cells (which harbor a 5q31 deletion encompassing CTNNA1) suppressed cellular proliferation though enhancing apoptotic death (Liu et al., 2007).
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