Sentence examples for suppressing activation from inspiring English sources

Thus, tumor cells may use this pathway not only to escape immune response by suppressing activation and expansion of tumor-infiltrating T cells but, potentially, to actively support their growth by triggering mTOR signaling in trans in neighboring tumor cells thereby creating an intra-tumoral growth signal.

If procaspase-3/9 in starfish oocytes was blocked by such endogenous inhibitor proteins, recombinant procaspase-3/9-His6 mabsorborb the possible inhibitors suppressing activation of endogenous procaspase-3/9.

We observed that allogeneic Tregs were very potent in suppressing activation of both autologous and allo-specific CD4+ T cell proliferation (Figure 2B).

Notably, in the absence of C1q, HA induced STAT3 activation in DU145 cells (Fig. 10C and 10D), implying that HA may increase metastasis of C1q-deficient prostate cancer cells by upregulating STAT3 phosphorylation and suppressing activation of p53 and WOX1.

Therapies target VEGFRs by suppressing activation signaling of VEGFR can also effect.

The three compounds exhibited similar potency in suppressing activation of VEGFR-2 and PDGFR- β (Table 3).

Retinoic acid acted on DCs to induce suppressor of cytokine signaling-3 expression, which suppressed activation of p38 mitogen-activated protein kinase and proinflammatory cytokines.

This treatment also suppresses activation of ERK1/2, p38 MAPK and MKK3/6; however, it upregulates MKK4 activity.

These results suggest that AT1 receptor blockade suppresses activation of C1q-Wnt/β-catenin signaling pathway in injured skeletal muscle.

Aghai, Z. H. et al. Azithromycin suppresses activation of nuclear factor kappa B and synthesis of pro-inflammatory cytokines in tracheal aspirate cells from premature infants.

Deng, Z. B. et al. Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells.