Sentence examples for suppressed responsiveness from inspiring English sources
In conclusion, suppressed responsiveness of melanoma cells to TRAIL appeared as based on three main antiapoptotic regulation steps, namely (i) high levels of antiapoptotic Bcl-2 proteins, (ii) high levels of cIAPs and (iii) suppressed Bax activation.
When delivered intravenously or subcutaneously, the liposomes targeted antigen-presenting cells including DCs, macro-phages and B cells in situ, suppressing responsiveness to NF-κB and inducing antigen-specific Tregs.
In conclusion, we report dose-dependent suppression of mTOR activity by IL-6 and suppressed mTOR responsiveness to glucose administration in Apc(Min/+) mice.
In conclusion, suckling suppressed pituitary responsiveness to exogenous GnRH challenge in post-partum buffaloes.
Other studies showed that pharyngeal aspiration of SWCNTs (40 μg/mouse) in BALB/c mice induced pulmonary inflammation and suppressed the responsiveness of T cell 7 days postexposure.
Further clinical details of this cohort are presented in Table 2. TCM used in these experiments suppressed the responsiveness of healthy control MDDCs to LPS as we have previously observed.
One of these (Sub1A-1) is a mutated form and responsible for suppressing ethylene responsiveness (Xu et al. 2006).
A recent study on an hPSC-based 2D gastrulation model demonstrated a direct connection between cell density and the spatial localization of cell surface receptors for transforming growth factor-β and BMP signaling, wherein high cell density facilitates the seclusion of receptors to cell cell contact and thus suppresses cellular responsiveness to soluble ligands14.
In vitro studies indicate that PRA blocks progesterone action by inhibiting the transcriptional activity of PRB [20] and consequently suppresses progesterone responsiveness.
Interestingly, besides inhibiting morphologic transformation of premalignant breast cells, reduction mammoplasty-derived fibroblasts were also found to have the ability to suppress estrogen responsiveness of premalignant breast cells.
Moreover, these Tr1 cells can suppress airway responsiveness and their development is dependent on IL-10 production by DCs, since adoptive transfer of DCs from IL-10 deficient mice fail to induce Tr1 mediated tolerance[ 22].
