Sentence examples for suppressed network from inspiring English sources

Exact(3)

Using networks of cultured cortical neurons, acetylcholine microinjections and a novel closed-loop 'synchrony-clamp' system, we found that acetylcholine pulses strongly suppressed network synchrony.

Activity levels in Mg++ 2.5 mM, Mg++ 5 mM and TTX 30 nM were not significantly different from each other and all strongly and nearly completely suppressed network activity.

The initial (approximately 10 hours) periods of suppressed network synchrony were not accompanied by reductions in mean firing rates as compared to pre-ACh applications levels, indicating that Sync Ratio values can change independently of changes in firing rates (compare Figure  3c and d).

Similar(57)

If they do, does this adaptation occlude the capacity of cholinergic neuromodulation to suppress network synchrony?

We then examined the ability of multiple neuromodulators to suppress network synchrony continually.

These findings indicate that the capacity of neuromodulators to suppress network synchrony is constrained by slow-acting, reactive processes.

Does NA also suppress network synchrony in a manner similar to the activities of ACh? Do cortical networks adapt to this neuromodulator as well?

In summary, these experiments demonstrate that withdrawing cholinergic input can restore the capacity of ACh to suppress network synchrony in subsequent periods.

Specifically, we examined the capacity of both fixed and feedback-based adjusted cholinergic input to suppress network synchrony continually as defined above.

The activation of these neuromodulatory systems strongly suppresses network synchrony and promotes asynchronous activity patterns typical of aroused and attentive behavioral states.

These findings indicate that prolonged cholinergic (and noradrenergic) input induce slow-acting reactive processes that reduce their efficacy and ultimately negate their capacity to suppress network synchrony.

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