Sentence examples for suppressed mainly from inspiring English sources

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Our results indicate that Ang-II is an active stimulant for the proliferation and fibronectin production of mesangial cells, and the effect is partly suppressed mainly by ET-1 type A receptor antagonists.

Moreover, lung metastasis of B16-F10 melanoma in 33D1+ DC-depleted mice seemed to be suppressed mainly by NK cells that might also be activated by IL-12 secreted via LPS stimulation.

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Additional ageing experiments at 240 °C showed that neither the Z phase or T phase are formed in the ternary alloy, but only precipitates of the S phase, while in the quaternary alloy the S phase is strongly suppressed and mainly Z phase precipitates are formed.

By using small hairpin (sh) RNA targeting Prdx1 mRNA (shPrdx1) in PTEN−/−MEFs, transformed by either H-RasV12 or ErbB-2/neuT, we showed that Prdx1 suppressed transformation mainly by regulating PTEN.

Suppressing SOD1 mainly in astrocytes led to preserved muscle innervation despite only partial protection of spinal motoneurons.

In fact, the role of antiapoptotic factors like Bcl-2, Bcl-XL, and Bcl-w is to suppress autophagy, mainly by interacting with Beclin 1 [ 12].

Although melatonin's ability to suppress angiogenesis mainly through VEGF downregulation has been shown in other tumour types (Lissoni, 2002; Kim et al, 2013), there are no reports about its anti-angiogenic activity in liver cancer.

Thus, aldosterone production is activated in the failing ventricle and is suppressed by perindopril mainly via the suppression of cardiac ACE activity in patients with heart failure.

Taken together, MHC I + IL-2/anti-IL-2 pre-transplantation mainly suppressed CD8+ T cell proliferation in the grafts, whereas MHC II + IL-2 pre-transplantation mainly inhibited CD4+ T cell proliferation.

Meanwhile, as the thickness of the organic shell is increased to 80 nm, the reflection of P3HT/Si NWA system is suppressed, which stems mainly from the improved optical impedance matching between air and Si due to the presence of the additional low-index coating layer.

The crack propagation behavior was mainly suppressed by (1) high hardness and high compressive residual stress, and (2) the strain-induced martensite transformation of retained austenite and high internal stress resulting from a difference in flow stress between the soft martensite matrix and the finely dispersed hard MA-like phase that developed during fatigue deformation.

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