Exact(2)
The Nup62 FG gel was already more selective and clearly suppressed entry of mCherry and tCherry, resulting in partition coefficients of 0.7 and 0.6, respectively.
The fused domains now formed a gel that completely excluded tCherry and efficiently suppressed entry of mCherry (partition coefficient ≈0.2; Figure 4B).
Similar(58)
RfaH and its paralog NusG are thought to suppress entry into pauses by favoring forward translocation and can additionally inhibit hairpin-stabilized pauses by inhibiting RNAP clamp opening through an interaction of their NTDs with the clamp (Herbert et al., 2010; Hein et al., 2014).
Such demand means companies in popular sectors can suppress entry-level wages, and even just offer unpaid internships initially.
In contrast, siRNA targeted to Orai1 suppressed Ca2+ entry but not Ca2+ release, consistent with Orai1-dependent CRAC channels mediating Ca2+ entry (Fig. 1C and D).
We found that Ro5-4864 SOCprentry SOC entry, whereas intracellular Ca2+ release from the ER appeared unaltered.
The EdU cell proliferation assay determined that miR-145 and si-SENP1 suppressed the entry of PC-3 cells into S phase.
Further evidence for physiologically relevant KV1.3 came from intracellular Ca2+ measurement experiments where margatoxin significantly suppressed Ca2+ entry, consistent with the existence of a channel that contributes to the enhancement of the electrical attraction for the inward movement of the positively charged Ca2+ ion.
Binding of the NGN RfaH-NTD (cyan) to the clamp domain (pink) of RNAP inhibits clamp motion and suppresses entry into pause states (Sevostyanova et al., 2011 ).
We recently reported a protein engineering strategy, which we call "helix-grafted display", and applied it to the challenge of suppressing HIV entry.
The IN60 80 peptide does not directly suppress viral entry and RT enzymatic activity (data not shown).
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