Also, introduction of exogenous ubiquitin does not suppress developmental lethality caused by loss of endogenous USP5.
The discovery of a SirT1 function in suppressing developmental genes could be a further clue for the correct interpretation its role in cancer.
mTORC1 inhibition suppressed multiple developmental defects caused by apc mutation in zebrafish.
We found that RNAi by dsRNA injection of the C. elegans NPR2 homolog nprl-2 (F49E8.1) also suppressed the developmental arrest of elo-5 larvae.
dlk-1 (lf) mutations strongly, but partially, suppress developmental defects in rpm-1 mutants, such as impaired axon termination and synapse formation (Grill et al. 2007; Nakata et al. 2005).
The socA locus was initially identified by mutations that partially suppress the developmental defect of a csgA mutant [ 108].
Because strong unc-112 mutants are very sick and develop extremely slowly, we performed our unc-112 epistatic studies in a dim-1 mutant background that suppresses the developmental delay of unc-112 mutants but has no visible effect by itself on engulfment (Table 1).
They also grew a rat gall bladder inside a mouse embryo, even though rats don't grow gall bladders during normal development — suggesting that rats have the genetic coding for gall bladders but those genes are suppressed by their developmental environment.
Looking at Figure 2 reveals that it is strongly suppressed on the developmental series of experiments related to shoots and stems, but expressed on experiments for responses to bacterial derived elicitors.
Limited success and high costs, however, suppressed interest in continuing developmental efforts.
Therefore, carbohydrate transport from vegetative to reproductive tissues was likely to be slightly suppressed at early anther developmental stages, and carbohydrate and lipid metabolism was abnormal in the MES-treated planthersthers.
