Exact(4)
Dr. Jentzen said he became aware in 1995, when 90 people died in a July heat wave, that 16 victims who had taken medication for anxiety and depression died after these drugs appeared to suppress their ability to dissipate heat through perspiration.
Here, we show that non-tumorigenic human mammary epithelial cells (MCF10A and HMEC) secrete factors able to enhance the proliferation of estrogen receptor α (ERα) positive breast cancer cells (MCF7 and T47D) and suppress their ability to undergo apoptosis.
There is no legitimate reason he would be giving women Quaaludes before sex except to suppress their ability to consent," he said.
These two mechanisms could be modified by substances, such as drugs and plant constituents, to either enhance or suppress their ability to resist invasion by pathogens [ 1, 2].
Similar(54)
Furthermore, siRNA-mediated knockdown of ERK5 in A375 cells also significantly suppressed their ability to form invadopodia.
Targeting survivin-ΔEx3, rather than survivin alone, may selectively and effectively destroy tumour cells, by suppressing their ability to resist apoptosis.
Taken together, these data indicate that BTK knockdown in MM cells promotes their growth in a supportive in vivo microenvironment but suppresses their ability to metastasize to new BM niches.
On the other hand, depletion of p130Cas/BCAR1 expression in transformed mammary cells increases the activation of Smad2/3 and suppresses their ability to invade in response to TGF-beta [ 9].
We have previously reported that irradiation of the abdomen of mice before i.v. injection of both immunogenic and nonimmunogenic tumour cells is capable of suppressing their ability to form metastatic lung nodules in a time and dose-dependent fashion.
Knock down of CTGF expression in these primary human cardiac fibroblasts suppressed their ability to grow in medium containing serum and added supplements, and after 9 days in culture, the number of cells correlated to the amount of CTGF produced.
While there are many explanations for this apparent paradox, we considered the hypothesis that vascular ECs in adults are stable and quiescent because they produce a soluble agent that suppresses their ability to respond to LPA.
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