Sentence examples for suppress progression from inspiring English sources

Based on these findings, we have reason to hope that pharmacologic inhibition of linker phosphorylation might suppress progression to human advanced carcinomas by switching from protumorigenic to tumor-suppressive TGF-β signaling.

Importantly, genes associated with cancer progression (i.e., Itgb2, Itgb5, paxillin, fyn) displayed increased expression, whereas those thought to suppress progression (i.e., vinculin, gravin) exhibited decreased levels of expression compared to MOSE-E cells.

Taken together, these data suggest that CD44 may represent a novel point for intervention to suppress progression of endocrine-resistant breast cancer.

Therefore, whether comprehensive suppression of TGF-β signalling promotes or suppresses progression of malignant tumours depends on various factors, including tumour origin, pathological type, and microenvironment.

Treatment with T0901317 liposomes suppressed progression into S phase, causing an increase in the G0/G1 population (75.3 ± 3.2%).

We show that Erk5 signaling maintains ESCs in the naive state and suppresses progression toward primed pluripotency and neuroectoderm differentiation.

In this chapter, we review current understandings of the diverse roles played by CD4+ T helper cell subsets in either promoting or suppressing progression of solid tumors.

p16INK4 binds to and inhibits CyclinD & CDK4/6 complexes which suppresses progression from G1 to S transition.

Some success has been achieved in suppressing progression of periodontitis by mechanically removing bacterial biofilm, the very cause of the disease.

The present in vivo study demonstrated that intraarticular injection of hyaluronan suppressed progression of osteoarthritis.

MitoVES also suppressed progression of tumours derived from both adherent and sphere cells, with similar efficacy.