Exact(1)
Finally, the possibility to suppress problematic overeating of palatable sweet foods using GHS-R1A antagonists may have clinical and therapeutic relevance for the emerging beneficial effects of such compounds for blood glucose control (Sun et al. 2006) in type 2 diabetic patients (Esler et al. 2007).
Similar(58)
Members of the audience, however, were left to formulate their own theories about what might have motivated the authorities to suppress the absorbing, problematic work.
Another obvious advantage of inducing antigen-specific therapeutic responses is that Th1 responses to other antigens and pathogens such as mycobacterium should not be suppressed, which reduces the problematic augmented risk of infection that a non-specific approach carries [13].
The kinase-mediated double role feature makes targeting GSK3 catalytic activity potentially problematic since it suppresses GSK3-mediated degradation of β-catenin, thus activating Wnt signaling therefore being potentially oncogenic.
Their continuing involvement in providing the moral support and implicit endorsement of an authoritarian regime that is perceived to have relied on foreign (Saudi) forces to suppress its own citizens is deeply problematic.
The overactivity phenotype may also suppress c-myc, but this is problematic as c-myc is pro-proliferative.
I for one look forward to a novel legal defense arguing that the secular authorities should recuse themselves entirely from his case because of their long problematic history of misunderstanding and suppressing God's prophets.
Furthermore, genetic and pharmacological studies have suggested that broad targeting of general TGFβ signaling pathways, although perhaps of benefit in suppressing aspects of the SSc phenotype, might be problematic for treating SSc due to the pleiotropic nature of TGFβ.
In addition, the two called the finale "problematic" because it featured Skinner and Doggett suppressing the truth, a thematic choice that goes against the spirit of the series.
However, the tension between the bones of fact and the fictional flesh can be problematic, as Leon Garfield argued: "Often you have to suppress what you actually know, and do it in a way that doesn't seem as though you're doing it, and you can only do that, I find, by being very subjective in your writing".
Reconstitution of WT mice with fetal derived KLF4−/− heme progenitor cells is also problematic, as it results in mice with greatly suppressed monocyte numbers [23].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com