Sentence examples for suppress expression of from inspiring English sources

To investigate the RAM domains governing nuclear entry, HeLa cells were simultaneously transfected with RAM siRNA to suppress expression of the endogenous protein and with pcDNA5-based constructs to express Fg-RAM WT and mutants.

An in vitro study has demonstrated that elevated CO2 levels suppress expression of TNF and other cytokines by pulmonary artery endothelial cells via suppression of NF-κB activation [ 18].

Gene therapy aims to either synthesize desired proteins (DNA delivery) or suppress expression of endogenous genes (siRNA delivery).

Design rules have improved, and it is now routinely possible to obtain reagents that suppress expression of any gene desired.

Furthermore, using antisense methods, we suppress expression of the Ii protein, that normally blocks the antigenic peptide binding site of MHC class II molecules during synthesis in the endoplasmic reticulum.

Concordantly, when RNA interference was used to suppress expression of beta-arrestin2, but not beta-arrestin1, LDLR endocytosis was reduced.

Furthermore, astrocytes have been reported to suppress expression of iNOS [57], [58].

p53 can activate or suppress expression of its target genes in a number of ways.

This sequence was transfected into rat hippocampal neurons to suppress expression of endogenous NLG-1.

Dominant-negative Gli2 is able to suppress expression of neurogenic bHLH factors and delay neurogenesis.

In this study, we provide evidence that β-catenin lies downstream of WNT4 to suppress expression of activin βB.