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RfaH and its paralog NusG are thought to suppress entry into pauses by favoring forward translocation and can additionally inhibit hairpin-stabilized pauses by inhibiting RNAP clamp opening through an interaction of their NTDs with the clamp (Herbert et al., 2010; Hein et al., 2014).
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Such demand means companies in popular sectors can suppress entry-level wages, and even just offer unpaid internships initially.
The Nup62 FG gel was already more selective and clearly suppressed entry of mCherry and tCherry, resulting in partition coefficients of 0.7 and 0.6, respectively.
The fused domains now formed a gel that completely excluded tCherry and efficiently suppressed entry of mCherry (partition coefficient ≈0.2; Figure 4B).
Binding of the NGN RfaH-NTD (cyan) to the clamp domain (pink) of RNAP inhibits clamp motion and suppresses entry into pause states (Sevostyanova et al., 2011 ).
The IN60 80 peptide does not directly suppress viral entry and RT enzymatic activity (data not shown).
According to this hypothesis, the blockade of the KV1.3 K+ channels should suppress Ca2+ entry, which is what we observed.
Curcumin inhibit tumor cell growth and suppress cellular entry of viruses very potently, and is efficient in suppressing phorbol-ester-induced tumor promotion.
Instead, MRP2 in hematopoietic cells or their precursor cells is likely to suppress the entry of docetaxel into cells and protects them against its cytotoxicity.
Our simulations suggest that summation of single excitatory and inhibitory synaptic currents may reduce dendritic excitation and suppress calcium entry via NMDA receptors (Larkum et al., 2009).
In the adult cortex, NPY is exclusively expressed by a subset of GABAergic interneurons (Hendry et al. 1984) and NPY acts on G-protein coupled receptors to suppress calcium entry into neurons.
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CEO of Professional Science Editing for Scientists @ prosciediting.com