Sentence examples for suppress cell differentiation from inspiring English sources

Furthermore, in vitro, depending on the cellular model analyzed, p53 can either facilitate or suppress cell differentiation.

5) While the Nup98-HoxA9 stablESES cell lines show an altered morphology and a decreased spontaneous differentiation, the fact that Hox genes expression is altered does not prove that Nup98-HoxA9 doesuppressess cell differentiation in ES cells" (see impact statement).

Inhibition of RANKL-induced [Ca2+]i oscillations and NFATc1 activation suggests that POEE may suppress cell differentiation into osteoclasts, whereas altered internal Ca2+ mobilization in response to a low concentration of ATP suggests that POEE may work in a different way.

36 Therefore, our finding that expression of Dp53 suppresses cell differentiation is consistent with the inhibitory role of ΔN isoforms in cell differentiation.

Taken together, the results of these studies suggest that Notch/Jagged signaling promotes the maintenance of the progenitor phenotype and even suppresses cell differentiation.

So, the negative modulation of Mef2c expression by Tbx1 could contribute to explain the role of Tbx1 in suppressing cell differentiation (14).

SKI and SMAD4 cooperatively suppress TH17 cell differentiation.

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.

Huh, JR, Leung, MWL, Huang, P, Ryan, DA, Krout, MR, Malapaka, RRV, Chow, J, Manel, N, Ciofani, M, Kim, SV, Cuesta, A, Santori, FR, Lafaille, JJ, Xu, HE, Gin, DY, Rastinejad, F, and Littman, DR. "Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity". Nature 472, no.

(F ) DYRK inhibitors suppress Th17 cell differentiation.

IFN-γ could differentiate naive CD4+ T cells (Th0 cells) into Th1 cells, while suppress Th2 cell differentiation [ 31, 32].