All these considerations have led us to suppose that the effects exerted by estrogens on macrophages during experimental paracoccidioidomycosis may involve a multi-event process, which includes: (a) altered expression of glycans on the host cell surface; (b) augmented interaction with a GlcNAc binding fungal lectin; (c) enhancement of nitric oxide production by macrophages.
However, there are reasons to suppose that the effects, "undesirable" during a certain period of time, may be eliminated by other factors.
However, as the prediction of female early onset breast cancer based on a family history of breast cancer will be especially important for younger women, we suppose that the effects are marginal.
From a pathophysiological point of view, we suppose that the effects of IABP (increased coronary perfusion, reduction of left ventricular afterload) might induce the greatest effect in patients with critically reduced coronary perfusion and (temporarily) severely reduced left ventricular function; that is, in patients with acute myocardial infarction who need to be temporized prior to CABG.
Suppose that the effects of genetic buffering (g) are similar between singletons and duplicates, as long as they have a similar d N / d S ratio; we designed a simple procedure as follows to take the effect of sequence conservation into account.
Supposing that the effect is direct, it would be important to identify the primary site of action of such antagonists in neural networks, which are mainly composed of GABAergic, glutamatergic neurons, and glial cells.
Because the primary hypothesis supposes that the effect of genotype can be seen most strongly (or only) in subjects exposed to stress, analyses including only these datasets may have particular power to detect the hypothesized effect.
It can also be supposed that the effects of further causal factors like, for instance, large scale geological differences, are accounted for by the regional location proxy variable.
The regression model applied in this study supposed that the effects of decreasing and increasing the home-cage activity in the chromosome regions partitioned into different strains are summed over the entire strain.
We suppose that the smoothing effect is connected with the amorphization of Al films in the presence of Si.
