These studies suggest that, despite recent evidence supporting the avoidance of over-sedation [ 57, 58], the use of systematic approaches to measure sedation state and optimise sedation for individual patients is not universal.
As it is recognized that one of the corner stones for the containment of AR is the appropriate prescription of antibiotics in the outpatient sector [ 28], this finding could support to the avoidance of prescription of broad-spectrum antibiotics to treat S. aureus infections in the community.
Particularly, this finding could lend support to the avoidance of prescription of broad-spectrum antibiotics to treat S. aureus infections in rural community settings.
As it is recognized that one of the corner stones for the containment of antibiotic resistance is the appropriate prescription of antibiotics in the outpatient sector, this finding lends support to the avoidance of prescription of broad-spectrum antibiotics to treat S. aureus infections in the community.
Goffman believed when a trait turns "those of us whom he meets away from him", a person is the victim of stigmatisation in its purest form (p.15) [ 1], and this strongly supports the existence of the Avoidance component that is included in the scale.
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Nalmefene plus psychosocial support led to the avoidance of 7179 alcohol-attributable diseases/injuries and 309 deaths per 100 000 patients compared to psychosocial support alone over the course of 5 years.
Nalmefene plus psychosocial support led to the avoidance of 7179 alcohol-attributable diseases or injuries and 309 deaths per 100 000 patients versus psychosocial support alone at 5 years, which represents a considerable benefit.
After 5 years, nalmefene plus psychosocial support led to the avoidance of 7179 955% CI 4244 to 12 654) alcohol-attributable diseases or injuries and 309 (95% CI 181 to 641) deaths per 100 000 patients versus psychosocial support alone.
The exploratory analysis modelling the 'no treatment' arm demonstrated the important public health benefit for patients entering treatment for alcohol dependence: compared with 'no treatment', nalmefene plus psychosocial support led to the avoidance of 20 202 (95% CI 13 942 to 27 243) alcohol-attributable diseases or injuries and 864 (95% CI 558 to 1469) deaths per 100 000 patients.
