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Our results suggest that the N-terminal α-helix supports the activation of PLA2 by (a) enhancing the membrane binding strength, (b) facilitating a productive-mode orientation of PLA2 at the membrane surface, and (c) conferring conformational integrity and plasticity to the enzyme.
The second is an adaptive or intelligent tutoring system, which supports the activation of metacognition and information retrieval.
A huge amount of experimental data supports the activation of the transcription factor NF-kB as a key redox-sensitive event associated with vascular dysfunction (reviewed in 7).
One possibility is that ULK1 supports the activation of STK38 by MOB1, MST1/2, and/or yet to be identified upstream regulators of STK38 upon autophagy induction.
The increase in expression of CK1alpha (CSNK1a1), a critical regulator of the APC destruction complex [ 41] supports the activation of the canonical Wnt pathway in response to Tamoxifen [ 42].
In a recent publication, a second talin-binding site has been mapped on the β subunit that, together with the PIPK1γ site, supports the activation of integrin (Wegener et al, 2007).
Similar(53)
- Using an unbiased approach, we biochemically isolated and defined an activity that supported the activation of pro-apoptotic BCL-2 proteins at the OMM.
Recent studies support the activation of apoptotic pathways in the Alzheimer's disease (AD) brain.
No evidence supporting the activation of desaturase expression could be found.
These results suggest that co-injected single-stranded oligodeoxynucleotides (ssODNs) as donor templates preferentially support the activation of HDR relative to the non-homologous end-joining pathway.
DNA electroporation used to deliver plasmids in vivo, induced type I interferons, thereby supporting the activation of innate immunity.
More suggestions(15)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com