This finding supports further evaluation of S100A6 as a prognostic biomarker in CCA.
In summary, this study supports further evaluation of the RTS,S/AS01E candidate vaccine with both 0,1,2- and 0,1,7-month schedules in infants, and when co-administered with standard EPI antigens.
Thus, our data supports further evaluation of MSC as a HIF-α inhibitor in combination with multikinase inhibitors, like sunitinib, to determine their efficacy in ccRCC xenograft model.
The possibility to perform chemosensitivity tests using semiautomated microtiter plate technology supports further evaluation of this system as an alternative antitumour drug testing model.
The preclinical evidence presented here supports further evaluation of either gemcitabine alone or in combination with DMAPT or related agents as intervention to delay the progression of pancreatic cancer.
Although larger studies will be needed to assess the value of PET in the setting of response evaluation, the fact that 4 of 5 patients with negative post-therapy PET are in first continuous CR supports further evaluation of PET scan also in this context.
