In the study by Johansson and colleagues [ 51], nurse managers who had a superior that stressed the importance of EBP reported a significantly higher number of activities in connection with introducing and discussing research findings with staff members, and also used research findings in quality improvement to a higher extent than nurse managers with less supportive superiors.
Through an encouraging and supportive attitude, superiors can strengthen their subordinates' self-efficacy and thus foster personal efforts for the achievement of organizational goals: the "can-do" component of motivation.
In advanced gastric cancer, first-line use of palliative combination chemotherapy compared with best supportive care is superior in terms of quality of life and overall survival.
A Cochrane Database review of six clinical trials (649 patients) confirmed that TPE is superior to supportive care across multiple functional outcome measures [ 17].
The reviewers concluded that TPE is "the first and only treatment that has been proven to be superior to supportive treatment alone," and should be regarded as the standard against which new treatments should be judged [ 17].
10 13 In cases of intolerance to MTX or where continued use of MTX is no longer appropriate, TCZ has supportive evidence to be superior to MTX or other csDMARDs.
Recently, in a double-blind study, maintenance MTA plus best supportive care cohort showed superior progression-free survival and overall survival when compared with placebo plus best supportive care in patients whose disease had not progressed after four cycles of platinum-based doublet induction chemotherapy [ 1].
None of the interventions studied were superior to supportive therapy in patients with Stx-HUS. 2 No RCTs specifically evaluating the effectiveness of any intervention including PE or PI were found for patients with aHUS. 2 Eculizumab is a new therapy being tested in patients with aHUS.
(He was hardly the only one, of course, who might have had a hard time comprehending the ultimate outrage -- of how a Boston priest who actually gave speeches at the North American Man-Boy Love Association and ended up running a gay, clothing-optional inn in Palm Springs, Calif., could have been receiving supportive notes from his superiors).
Azacitidine was superior to best supportive care and low dose chemotherapy in terms of quality-adjusted life-years gained, 1.82 and 2.03, respectively (life-years 2.16 vs. best supportive care, 2.39 vs. low dose chemotherapy).
