Although most of the supportive data in this area have been derived from cancers that classically overexpress EGFR (notably including head and neck squamous cell carcinoma), there is early evidence of equivalence in breast tumour cells, in which EGFR overexpression can be more modest.
This important issue has implications for individuals stopping sunitinib for significant periods of time and requires further evaluation, especially in light of the supportive preclinical data in this area [ 19].
"I think that, generally, leadership in the Assembly is supportive of moving forward in this area," Mr. Bing said.
The international community, increasingly aware of the importance of education in countries recovering from crisis, has been supportive of UNICEF's efforts in this area.
Recent meta-analyses find a strong evidence base to support consumption of fibre-containing foods for prevention of several cancers [ 2], and the majority of studies in this area are supportive.
However, the United States risks its leadership in this area if the supportive ecosystem to enable its translation into commercialization isn't there.
Other reviews in this area are broadly supportive of interventions to promote information gathering by patients, identifying a range of beneficial outcomes.
While the close association between fatigue and depression suggests that antidepressants may have a role in treating cancer-related fatigue, research in this area has not been supportive of this class of medications.
"Our opinion is mostly unfavorable of their general strategy," he said, noting that while his group opposed same-sex marriage and federal court overreach in this area, it is generally not supportive of efforts to nullify federal law.
CPH staff members' lack of knowledge and skills in supportive supervision suggest that there is room for improvement in this area and that this might have a positive impact on provider motivation.
