Bioinformatics analyses and CAD association analysis provided supportive evidence and functional information on the association of several of these genes with BP, e.g., ATXN2, CLCN6, CYP17A1, FURIN, HECTD4, ID1, NPPA, and PTPN11.
The matrix management is advocated with strong programs organized by cross-functional teams and supportive functional departments providing programs with the resources they require (qualified people, tools, and generic practices, as well as test laboratories).
This is consistent with data indicating that MPs produce trophic factors which play an important supportive role in the repair and functional recovery of normal skeletal muscle (Saclier et al, 2013).
Neuroendocrine tumours were confirmed in these patients by histological diagnosis; where this information was not available, the diagnosis was based upon elevated biochemical markers (including chromogranin A and/or 24 h urinary 5HIAA) plus cross-sectional (CT/MRI) and functional imaging supportive of a NET (positive uptake on OctreoScan/DOTATATE scans) (Covidien; Petten, The Netherlands).
Staff shortages, transportation, inadequate supportive supervision, and a lack of essential supplies and functional equipment are notable factors of the working environment that contribute to dissatisfaction.
Immunohistochemical analysis and functional in vitro studies are supportive of a causal role for the mutated DSG2 ICS domain in ARVC.
Thus, although several non-clathrin endocytic pathways have garnered varying degrees of supportive evidence, none has been unambiguously established in molecular and functional terms.
Correlating with clinical parameters such as prognosis and therapeutic responsiveness can be supportive of functional relevance of a mutated gene or pathway/network.
Participants were recruited from patients referred to a hospital-based multi-disciplinary supportive care team specializing in treatment of patients with nutritional depletion and functional decline.
Before the mid-twentieth century, the treatment of tuberculous spondylitis was primarily supportive and typically resulted in dismal neurological, functional and cosmetic outcomes.
