Sentence examples for supporting this functional from inspiring English sources

To date, however, none of the SALMs has been characterized in knockout mice; thus, in vivo data supporting this functional diversity are lacking.

Concerning the rewarding aspects of sexual behavior and the involvement of opioids, a similar series of papers and reviews is available to support this functional relationship [ 166, 167, 247– 247].

Further evidence to support this functional interaction was obtained by the demonstration that the SK1 inhibitor, SKi, reduced SK1 expression and decreased the S1P/S1P4-induced stimulation of ERK-1/2 in MDA-MB-453 cells.

Supporting this hypothesis, our functional characterization using the Rb flux assay demonstrated that ADP and NAD+ are the likely ligands for GsuK as discussed below.

Previously defined patterns of gene expression across 3T3-L1 differentiation (Mikkelsen et al., 2010) further support this emerging, functional distinction of early and late ZEB1 enrichment.

Genetic deletion of NOS3 greatly reduced survival in female mice with pneumonia, and transgenic overexpression of NOS3 increased bacterial clearance in male mice, supporting the functional importance of this pathway.

The sequence-complementary mechanism of miRNA activity exploits combinatorial diversity, a property conducive to network-wide regulation of gene expression, and functional evidence supporting this hypothesized systems-level role has steadily begun to accumulate.

However, functional experiments supporting this hypothesis are still missing.

Despite the above evidence suggesting a role for c-Yes in CRC, functional data supporting this notion are missing.

Supporting this line of communication being functional, when studied in the presence of a cholinergic agonist, depolarization (for 1 s) of the postsynaptic neurone caused a transient (∼20 s) suppression of GABAergic inhibitory postsynaptic currents (IPSCs), an effect mediated through NO receptors and cGMP (Makara et al., 2007), with endocannabinoids also being intimately involved (see below).

This further supports the functional relevance of this endogenous antioxidant and gives novel insights into the mechanisms of probiotics.