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Together, these data suggest that helper T cells were critical for supporting the size of the CD8+ T cell compartment through mechanisms acting early in the T cell response, potentially by inducing CD25 expression on the anti-parasite CD8+ T cells.
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Tax revenues, he argues, will no longer support the size of state that Brownite social democracy created; meanwhile the state-provided services are destined to be inefficient and in need of ever larger dollops of cash.
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While helper T cells clearly supported the size of the effector CD8+ T cell pool, the CD4-dependence for survival was not absolute, as helpless T cells were readily detected at ten and thirty days post-immunization (Figure 2A, 3A).
This relative reduction was similar to the 78% reduction observed at day 10 (Figure 2A), suggesting that helper T cells do not affect the size of the CD8+ T cell pool that transitions from effector cells into memory cells and appear to only support the size of the early effector pool.
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