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This mini-review aims to summarise the evidence supporting the extent, causes and consequences of intra-tumour heterogeneity, and will suggest how this knowledge may be integrated into future clinical practice and research efforts to optimise patient care and clinical outcomes.
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The increased internal validity that is achieved when the results are based on trials with a higher degree of bias control supports the extent to which the overall results may be extrapolated to clinical practise.
International guidelines on biosimilarity [ 3– 5] outline that the approval of biosimilars must rely on the demonstration of comparability towards the reference product, starting with an exhaustive physicochemical and biological characterization whose results will provide evidence to support the extent of additional clinical evaluation [ 6– 8].
The current on the power line and the vibrations of the injector housing have been sufficient to diagnose the subassembly, thus supporting the decision on the extent of the repair.
Although there is some evidence supporting the latter proposition, the extent to which signal synthesis enzymes contribute to achieving tight quorum sensing signal specificity is unknown.
The results (Fig. 2C) showed that the C3-immunoreactive area was smaller in MBL-null (n = 5) than in WT (n = 5) mice, thus supporting that the extent of complement activation was milder in MBL-null than in WT mice.
Finally, it is measured the extent of supporting the detailed processes in the core manufacturing processes for each industry by IT (the extent of IT convergence).
Cuccinelli is pro life, pro drilling, and pro gun, even to the extent of supporting the legality of one carrying a licensed concealed handgun into a club or restaurant, provided (small comfort) that the person does not imbibe.
In three of the four brands that supported growth, the extent of growth was enhanced by incubation at 28 °C.
The strength of the conclusion is, of course, more supported to the extent that such examples are multiplied.
Thus it at least indirectly supports, to the extent it is needed, the moral character-formation on the humanistic level which is emphasized by Western personalism.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com