In contrast, most cells derived from E11 murine brain stained positive for TUJ1 (Fig S9B of Supporting information, left panel).
In embryonic pancreatic development, GFAP expression, representing the α cell population, was observed in cells derived from embryonic day 11 (E11) murine pancreatic buds (Fig S9A of Supporting information, left panel), where no TUJ1-positive cells, representing a β cell population, were detected.
Because of either high cytotoxicity (≤20 μM) of the small molecule on the 293T cells or low efficacy (≥20 μM) of the small molecule within the viral replication assay 75 of the 78 compounds were discarded (Table S2, Supporting Information) leaving compounds A1895, R0529, and NSC260594 (Table S1, Supporting Information).
Images were color coded to reflect the intensity of uptake (Supporting Information, Figure S6, left).
Four families were solved in other research studies (Supporting Information, Table S1) leaving 22 families unsolved.
In total, 65 of 623 (10.4%) GF-regulated genes were affected by ICI treatment (Figure 3A top and 3B left; Supporting Information Table S3).
In addition, the Cry1C-resistant strain of P. xylostella was able to complete development when reared on Cry1C broccoli leaves (supporting information, Figure S1).
Inactivation of TSC22D4 again triggered an increase in serum TG levels (Supporting Information Fig S3M), while leaving serum cholesterol levels unaffected (Supporting Information Fig S3N).
Despite the same rate of metastatic incidence, mice inoculated with ΔN90-expressing cells (N90 and N90/NDRG1) developed distant metastases at a much earlier stage compared to the parental WB1-1 cells (Fig 5A and D left panel, Supporting Information Fig S4B), and they also formed significantly larger metastatic lesions (Fig 5C, D right panel).
As noted in a blog post at ChemBark, the authors of an article published in a chemistry journal seem to have done something similar, but worse: A note was left in the supporting information that seems to instruct the primary author to fabricate data.
After removing those with sequence identities >40%, the proteins left were listed in Supporting Information S5, S6, respectively.
