ToxRefDB and related databases will help support computational analysis and modeling of the links from molecular interactions through cellular and organ phenotypes all the way to whole-animal toxicity.
A competition experiment with paclitaxel showed that paclitaxel reduced the binding of GF to tubulin in microtubules supporting the computational analysis data that GF binding site partially overlaps with the paclitaxel site in tubulin.
The developed system is organized in three modules: the first and second modules model the ontology of a responsive environment and the layout of an urban environment while the third module is a spatial database that supports further computational analysis of urban forms.
These observations were supported by computational analysis of the S100A8/A9 calcium-dependent aggregation propensity profiles.
The experimental observations were also supported by computational analysis of aggregation propensity profiles, demonstrating that the aggregation-prone regions are located in close proximity to the calcium- binding sites in both proteins.
Confero provides a unique and flexible platform to support downstream computational analysis facilitating biological interpretation.
This software platform was originally developed to support the computational analysis of shotgun genome sequencing projects [ 33].
This conclusion was further supported by a computational analysis [36]. Figure 8 shows that RANSAC's prediction is in line with this proposition (i.e., to achieve relatively high IQE values, the thickness of the (Co_{3} O_{4}) layer must be low, smaller than 150 nm and this property is also influenced by the thickness of the (MoO_{3}) layer).
Four of these categories comprise exclusively manually-curated associations supported by experimental, computational analysis, author statements or curatorial statements.
As a result, FYPO supports sophisticated querying, computational analysis and comparison between different experiments and even between species.
