Sentence examples for supporting a dose from inspiring English sources

There is, however, currently no evidence supporting a dose reduction strategy in patients with variant CDA genotypes.

This is distinct from the regulatory approvals and likely represents the lack of data supporting a dose response for these agents.

While one follow-up study found a beneficial effect of coffee [4], some but not all prospective and epidemiological studies have shown an association of coffee drinking with increased cardiovascular morbidity and mortality [1], [5] [8] with some results supporting a dose-dependent risk of a cardiovascular event [5].

Intermediate levels of GRN protein were observed in FTLD-U patients heterozygous for rs5848 supporting a dose-dependent decrease of GRN with each T-allele (data not shown).

Further supporting a dose-dependent effect on intelligence in adults, increased levels of occupational lead exposure have been associated with lower overall cognitive scores and intelligence scores [ 49].

Furthermore, intermediate levels of GRN protein were observed in FTLD-U patients heterozygous for rs5848 supporting a dose-dependent decrease of GRN protein levels with each T-allele.

Diabetes risk was higher in those who had taken more doses, supporting a dose-response association (200 399 daily doses: 1.7%, ≥400 daily doses: 2.3%).

After adjustment for all baseline covariates and exclusion of obese participants at phase 1, the corresponding mean differences were 0.19 (0.03 to 0.35), 0.38 (0.16 to 0.59), and 0.40 (0.09 to 0.72), again clearly supporting a dose-response association (P for trend<0.001, n=3957).

However further analyses by job and exposure duration did not support a dose response.

These PK and dose-escalation findings support a dose of 750 mg once daily as the recommended phase II dose.

No difference was found between once or twice daily dosing schedules and there was no evidence to support a dose response curve for the doses tested.