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ANOVA of region of interest measures supported this effect of prenatal treatment on lateral ventricle volume (F 2,19) = 5.39, p<.01) and subsequent post-hoc analyses confirmed lateral ventriculomegaly in offspring exposed to MIA on GD9 relative to control offspring (see Tables 1, 2 and Figure 1).
The microarray analysis supported this effect, showing an effect of FA on protein integrity and turnover that would be expected to have consequences for rates of somatic growth.
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Previous studies have indicated decreased TER in association with mannitol [27], but our own Ussing chamber measurements did not support this effect.
The reasons supporting this effect are not straightforward.
However, to date there is no evidence to support this effect.
Genomic data assessing myeloid cell factors support this effect (e.g., increased il6, il21, il23; Table S3).
In addition, overexpression of either the S83A-HP1γ or S83D-HP1γ mutant supports this effect in resultant cell cycle-related gene expression networks.
The Diabetes Control and Complications Trial appears to be the only study showing a relationship between glycemia and albuminuria, although a number of preclinical studies support this effect.
Individuals at high risk of falls at hospital admission could have their drug regimens re-examined in terms of drugs with additive adverse effects and simplified if possible before hospital discharge, if prospective studies support this effect.
Supporting this effect of the inflamed microenvironment on DC, when human blood-enriched DC are exposed colonic microenvironments from healthy controls 16 or non-inflamed areas from UC patients 28 they acquire an immature phenotype.
Some specific biological mechanisms supporting this effect have been elucidated: in animals given surgery, a growth-stimulating factor was found in serum [ 9] and a switch of micro-metastatic foci to the angiogenic phenotype, due to withdrawal of an angiogenesis inhibitor from the primary tumour, was demonstrated [ 10].
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