Sentence examples for supported increased expression of from inspiring English sources

These phenotypes contrast with that of the K5-Tie2 model, where our immunophenotyping algorithm supported increased expression of transcripts associated with CD4+ T-cells, but did not provide evidence for increased expression of transcripts highly expressed in cells from the monocyte-DC/macrophage lineage (Figure 9).

Several recent reports have supported increased expression of TG2 in multiple cancer types, including breast cancer [ 7- 10].

The second line of evidence to support increased expression of hPGFS is a potential tumour marker and a drug target that came from the wide expression of this gene in tumour cell lines from many different tumour types.

The data supporting increased expression of IFNα and interferon-inducible genes in those diseases is less well developed than in the prototype systemic auto-immune disease SLE or in Sjögren's syndrome, which shares some autoantibody specificities and immune system alterations with SLE [ 16].

Our data supported these finding as increased expression of CD45RA andCD45RB was found, together with a trend towards lower CD45RO expression.

These cases support the hypothesis that increased expression of α-Syn causes disease.

With respect to the lens, the present investigation supports the hypothesis that increased expression of Aβ in the lens leads to amyloidogenic interactions with other structural proteins (e.g., αB-crystallin) within the cytoplasm of supranuclear lens fiber cells.

At the very least, these observations do support the hypothesis that increased expression of IL-4 (especially compared to other cytokines) in peripheral blood could serve as a surrogate marker for TB-related disease, and that its reduction may be an indicator of restoration of immune response following cure due to treatment.

This supports our result, that increased expression of S1P pathway members is involved in metastasis.

This supports the hypothesis that increased expression of ribosomal genes confers a growth advantage [ 37].

Because malonyl-CoA inhibits CPT1 activity, the increase of Cpt1b expression in WAT supports the trend of increased expression of Scd1 and Fasn, enzymes responsible for the catalysis of a rate-limiting step in the synthesis of fatty acids from malonyl-CoA.