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This initial experience with prucalopride treatment for severe chronic constipation supported further phase II investigations of prucalopride regimens in different forms of chronic constipation.
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Therefore, overall results do not support further phase III development of sagopilone in patients with CRPC.
The findings presented here support further phase I/II clinical trials of immunotherapy with young TILs in patients with NPC in the near future.
The findings support further phase II evaluation of DaunoXome alone and in combination with other standard non-anthracycline cytotoxic or novel targeted agents.
Nonetheless, stable disease at four cycles in more than half of the patients treated, supports further phase II evaluation of this combination in specific tumour types.
An observational cohort study examining the microvascular effects of erythropoietin is underway and the evidence would support further phase II and III clinical trials examining this molecule as an adjunctive treatment in sepsis.
The results from a phase 2 study with ceftolozane/tazobactam in combination with metronidazole in cIAI supported further development for this indication [ 18].
In addition, this global effect is supported further by the observation that EGC inhibit cell proliferation in part by inducing a cell cycle arrest in G0/G1 phase [ 11].
The data support further evaluation of the second-generation strains in a phase I clinical trial.
Taken together, the results of this Phase II study are encouraging and support further studies with OKZ in RA.
This evidence data support further testing of this combination in a larger randomized phase III clinical trial.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com