A negative ΔAICc value supports a single normal distribution and positive ΔAICc value supports a two-component distribution over a single-component [ 44, 89].
Pre-development kurtosis value of −0.325 (standard error of 0.972) with a skewness value of −0.157 (standard error of 0.501), and a post-development kurtosis value of 0.262 (standard error of 0.972) with a skewness value of 0.562 (standard error of 0.501) also support the assumption of a normal distribution.
A pre-development kurtosis value of 0.548 (standard error of 0.972) and a skewness value −0.999 (standard error of 0.501); and a post-development kurtosis value of −0.545 (standard error of 0.972) and skewness value of -0.415 (standard error of 0.501) also support the assumption of a normal distribution.
A Gaussian fit describes the data consistently, fulfilling the requirement of a normal distribution (Supporting Information Fig. S2).
In all cases, the tests (Kolmogorov-Smirnov, D'Agostino and Pearson, and Shapiro Wilk) failed to support a significant deviation from a normal distribution, which is what we reported in the paper.
However, we found that the observed sizes of COs were not consistent with a Normal distribution, supporting a mixture of COs resulted from both DHJs and SHJs, since COs from SHJs might have different ranges of lengths resulted from a different pathway [ 18].
The insert in Fig. 7A shows the distribution of reported crystallographic resolutions for all structures; the histogram followed roughly a normal distribution which supported our assumption that resolution was a random source of structural deviations.
Consequently, the observed number of clones lacking TdCRT1 hybridization is 642 times (16,751/26 = 642) the expected standard deviation for a normal distribution, strongly supporting the premise that the distribution of TdCRT1 is not random.
TUD profiles of all phage genomes combined follows a normal distribution, which further supports that tetranucleotide usage patterns are well-conserved across each bacteriophage studied.
Note that normalized intensities were approximated with a normal distribution.
