Withdrawal of VEGF-A causes endothelial cells (ECs) lacking support of pericytes to undergo rapid apoptosis while ECs with associated mural cells expressing molecules involved in vascular remodeling (including Angs) survive [4], [6] [8].
A classical example entails growth factor signalling which sustains neuronal survival and can trigger differentiation or even antagonize the effects of toxic insults, whereas neurons without sufficient trophic support are prone to undergo apoptosis, as it occurs in a developing nervous system [ 106, 107].
In neonates with CDH the presence of respiratory distress after delivery indicates severe pulmonary involvement that requires medical management which includes mechanical ventilatory support prior to undergoing surgical correction [ 1].
Given the proven benefits of MRI in screening for breast cancer in this population, these data point to the urgent need to provide timely information and support to women undergoing MRI.
Given the proven benefits of MRI screening in this population of high-risk women, these data point to an urgent need to develop and evaluate strategies of providing information and support to women undergoing MRI.
Poor insight into TB and its treatment meant that through no direct fault of their own, family members could not provide the right type of support to those undergoing treatment.
We propose that effective immunosurveillance of senescent cells in salamanders supports their ability to undergo regeneration throughout their lifespan.
In the vast IDP settlements in Khartoum state, UNICEF and partners are supporting IDP teachers to undergo an intensive course to upgrade their English language skills.
However, sometimes supporting a teacher to undergo a PhD programme means losing that teacher for some period of time (for example, to attend a programme abroad) or to lose it forever (for example, to occupy another position elsewhere).
In light of these observations, we propose that the effective immune clearance of senescent cells in salamanders supports their ability to undergo multiple rounds of regeneration through their lifespan.
