Overall, the Sicilian OA patients' odds ratio of 1.53 (confidence interval, 1.11 to 2.11) describes a positive association between rs143383 GDF5 and KL (KL ≤ 2 vs. KL > 2), a trend in line with Valdes and colleagues [ 48], supporting this variant as an OA progression marker.
The results support that this variant is a potential risk factor for IBD.
The functional analysis did not support pathogenicity of this variant.
However, if their mothers had plenty of social support, children with this variant were at no greater risk of shyness.
Genetic studies support the variant traits of Vibrio pathogens.
For the CD44-, 21.6% (967 of 4,476) of all reads support the variant allele.
Therefore, our analysis does not support the role of this variant in contributing significantly to maths abilities.
Nevertheless, the revised multifactorial data support the observation that this variant exhibits the same functional deficiencies as the A1708E variant, with a 96% posterior probability of pathogenicity.
Therefore, because lipid-depleted conditions mimic what occurs in vivo these data support the view that this variant is possibly causal of the FH phenotype, but the status of this variant is still unclear, and co-segregation analysis in the relatives of this patient may resolve this issue.
