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The Cancer Genome Anatomy Project (CGAP) was designed and implemented to provide public datasets, material resources and informatics tools to serve as a platform to support the elucidation of the molecular signatures of cancer.
Therefore, it is mainly suited to study the secondary metabolism of a biological system of interest rather than to support the elucidation of primary metabolism.
In order to obtain additional information that could support the elucidation of their possible function and contribution to confer protection against acetic acid in the S. cerevisiae haa1∆ mutant, a prediction of conserved functional domains [ 19] and transmembrane helices (http://www.cbs.dtu.dk/services/TMHMM/) was attempted.
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Following grounded theory techniques the data analysis began as soon as the first interview transcripts were written and further sampling supported the elucidation of ideas and developed provisional theory [ 56].
In this article, we present an overview of the information content of UniProtKB/Swiss-Prot to show how this knowledgebase can support researchers in the elucidation of the mechanisms leading from a molecular defect to a disease phenotype.
One good example supporting this expectation is the elucidation of the role of mitochondrial dynamics on ageing which was concluded from the identification of PaDnm1, a gene upregulated in the long-lived copper-uptake mutant grisea of P. anserina [29].
By looking at the event cost space and supported events, our tools allow the elucidation of the complex interplay between event cost assignments and event support under various ranges and constraints of event costs.
SH2 domain-based affinity chromatography combined with MS analysis allows for the rapid identification of tyrosine kinase targets in human cancer cells, which should facilitate the elucidation of new signalling mechanisms, support the identification of new biomarker candidates and potentially even point to novel therapeutic targets.
The elucidation of mechanisms of action to provide biological plausibility and support causality suggested by epidemiological associations is a priority in current research.
The focus of the present work was specifically on the elucidation of the role played by tungsten on the catalytic activity and selectivity of tungstated zirconia supported palladium (Pd-mWZ) for the aqueous phase hydrodeoxygenation (APHDO) of ethylene glycol (EG).
"I will publish whatever is necessary for the elucidation of the public," says Boris.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com