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2D and 3D molecular views, as well as tabular views (not shown), are provided to support the editing operations.
The strong bias to AG mismatches, the clustering pattern in genes, the neighbor preferences, the tissue specificity (irrespective of biological origin), the resulting recoding events towards the common amino-acid, etc., all these strongly support the editing sites found by the authors.
Chiang et al., [ 5] proposed three criteria to evaluate the editing sites of miRNAs, i.e., if (i) the relative level of editing is at least 5%; (ii) at least 10 reads support the editing site; and (iii) the editing site is not in the last two positions at the 3' end of mature miRNAs, then the miRNA position was considered to be edited.
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This indicates that the read coverage at these two sites may be not sufficient to identify the "edited" version of the RNA (according to [ 28], for h1.0, 11 of 301 EST sequences support the "edited" version; while for hmgn1, only one EST sequence supports the "edited" version).
Since launch the device has only supported the editing and viewing of PDF documents.
DL, BS and BG supported the editing of the manuscript and added important comments to the paper.
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Maybe the investigation of the distribution of the relative proportion of reads supporting and not supporting the edit could help here.
Hence exclusive expression of myc-tagged KREPA3 WT can support the normal editing in vivo.
Also, I'll be able to build a strong support network through the editing community".
In this paper, we present COE, a peer-to-peer collaborative ontology editor, which supports the creation, editing, sharing, and reuse of ontologies, implemented on top of a general-purpose peer-to-peer framework, COPPEER.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com