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Support synergy between food security and agricultural development endeavours with environmental protection and conservation of natural resources.
Although our focus was on understanding the mechanisms underlying the therapeutic efficacy of combination αCTLA-4/α4-1BB treatment in the context of FVAX, we did explore potential reasons for the failure of GVAX to support synergy between these antibodies (Figure 1).
Given the time, energy, and resources that foundations and public agencies invest in partnerships, a stronger knowledge base about programmatic design features that support synergy development could strengthen efforts to improve health through collaboration.
Many of the SRAP's successful synergies came about because the National Program Office staff adeptly spotted opportunities and resources to support synergy, brokered relationships, and more generally helped grantees understand, value and learn how to create synergies.
The presence of an additive interaction was confirmed in that the joint association was four times as large as what would have been expected to be on summing the individual risks of psychological distress and low peer social support (synergy index = 4.5, 95% CI: 1.3 14.9).
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We also cover the cultural methods that offer scope to support synergies between the aforementioned methodological combinations.
On the basis of variable expression of c-Kit and PDGFR in breast cancer and of in vitro data supporting synergy between imatinib and capecitabine, the Southwest Oncology Group conducted a phase II trial of the combination in metastatic breast cancer.
During HIV/cell fusion, the FP and MPER likely bind to the cell and HIV membranes, respectively, and higher fusion for FP-HM relative to HM supports synergy between these two regions, likely via membrane perturbations.
This will entail partnering with local partners working at field level, supporting synergies, documenting good practices, as well as piloting and documenting new activities (e.g. school or community gardens; community cooking demonstrations; linking mother support groups to farmer field schools...).
However, further investigation using separate agents, the iron chelator deferoxamine and the topoisomerase II inhibitor epirubicin, did not support any synergy for the interaction of iron chelation and topoisomerase II inhibition.
How does that fight support brand synergy?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com