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In essence, these complex systems support sequencing of, and navigation through units of content.
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Conventionally, these analytical models do not account for the complex loading and reacting conditions of umbrella arch support systems throughout the tunnel excavation and support sequence.
HS, AJ and RB provided bioinformatics support (sequence analysis, sequence comparisons and ORF annotation).
Therefore, fast and user friendly methods are needed to support sequence annotation at this stage.
In our previous work we found no statistical evidence to support sequence dependent bias [ 12].
For the reference sequence S15 and 10 support sequences from the corresponding RFAM family, DotKnot-PW returns pairwise predictions ordered by the combined free energy and similarity score.
Ambiscript is a graphically-designed nucleic acid notation that uses symbol symmetries to support sequence complementation, highlight biologically-relevant palindromes, and facilitate the analysis of consensus sequences.
For each reference structure with the 10 support sequences from the corresponding RFAM family, 10 predictions are returned ordered by the combined free energy and similarity score.
Note that this does not include the prediction for the support sequences from RFAM, as no experimentally determined structures are available.
The supporting sequencing files for Figs. 3, 4 and 5 are attached as supplementary files with the manuscript.
For example, does a fusion transcript present at higher molarity (higher transcript abundance) correlate with higher number of fusion-supporting sequencing reads?
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