Regarding to these concerns, we avoided multilayer comparisons and tried to limit the number of comparisons in order to be supported by our sample size.
This finding regarding social support may reflect the limitations of our sample size and the high levels of social support in this sample (mean = 37.1, with a total possible score of 45), limiting our ability to detect a significant relationship between social support and postpartum depression.
33 Indeed specificity and sensitivity calculations of our analysis results, even though our sample size was small, support the published findings, as the MiniLab® demonstrates a low sensitivity for co-trimoxazole tablets when compared with content analysis with HPLC.
Figure 1 provides evidence to support our initial hypothesis that sample sizes are related to the prevalence of the condition treated and anticipated recruitment difficulties.
There are no precise tests to develop sample size estimates for gene expression profiling, so we started with theoretical principles and then applied empirical observations to support the sample size for these experiments a priori.
The theoretical principles and the empirical observations used to support the sample size for these experiments a priori were essentially as we described before [ 40].
This design decision made it difficult to detect project impact as part of the evaluation, as the evaluation budget was not big enough to support a sample size with enough power to detect impacts if they existed.
The HUASs provided data that informed the design and conduct of the case-control study, such as whether each site's DSS population was likely to support the sample size requirements for the case-control study.
Therefore, the aims of this pilot randomised controlled trial are to (1) determine the feasibility, safety and perceived patient response to a combined tDCS and exercise intervention in knee OA and (2) provide data to support a sample size calculation for a fully-powered trial should trends of effectiveness be present.
The aims of this pilot study are to (1) determine the feasibility, safety and perceived patient response to a combined tDCS and exercise intervention in knee OA, and (2) provide data to support a sample size calculation for a fully-powered trial should trends of effectiveness be present.
