In support of this speculation, the number of GSR habituater and sensitizer subjects to the initial shock trial was 28 and 17, respectively, and to the first tone-alone trial 40 and 6, respectively.
Modeling results, however, also provide support for the speculation of Cui et al. (42) and Jordan et al. (3) that R352 and D993 could move together during the gating cycle and experience a Coulombic attraction that has important functional consequences.
However, there is little direct evidence in support of this speculation, especially at a large landscape scale.
In support of this speculation, Tat has been reported to be subjected to ubiquitination [ 2].
In support of this speculation, SIRT1 expression was found to be reduced in human skin tumors.
In support of this speculation, local regions of serially transplanted epithelial clones occasionally manifested focal regions of hyperplastic lobular development.
In support of this speculation, we note that our phenotypic data are consistent with those recently provided by the larger analysis performed in Zurich [ 32].
No direct evidence has been presented thus far in support of this speculation, however, experiments such as those shown in Figs. 9 and 10 do provide such evidence.
In support of this speculation, we have previously shown that introduction of a Cys substitution at this location has no effect on 5-HT or granisetron, but eliminates the allosteric effects of VUF10166 in heteromeric receptors.
In support of this speculation, Fujimoto et al. [ 39] have reported AT1 receptor over-expression in human pancreatic cancer tissues and AT1 receptor-mediated growth regulation in pancreatic cancer cells.
