Sentence examples for support normal thymocyte from inspiring English sources

However, PDK1 L155E cannot support normal thymocyte proliferation.

A PDK1 L155E mutant, with a disrupted PIF pocket can support normal activation of PKB and restore nutrient receptor expression and DP and SP thymocyte differentiation in PDK1-null cells.

Mice expressing RORγtM were resistant to EAE associated with defective TH17 differentiation but maintained normal thymocyte development and normal lymph-node genesis, except for Peyer's patches.

Various normal thymocyte populations were inoculated with HIV-1, including unfractionated (UF), CD3- CD4- CD8- [ triple negative" (TN ], CD4+ CD8+ [ double positive" (DP)] thymocytes, and thymocyte populations obtained by limited dilution cloning.

Transplanted Lmna-/ thymus lobes show good engraftment in wild-type hosts and drive normal thymocyte development.

Transplantation of Lmna-/ neonatal thymus lobes into syngeneic wild-type recipients resulted in good engraftment of thymic tissue and normal thymocyte development.

Very differently, WT of Rasgrp1Anaef thymi contain all normal thymocyte populations.

During normal thymocyte development there is a huge proliferative expansion of cells following the process known as TCRβ selection.

Arrest of differentiation program at specific stage of normal thymocyte development is a priming event in the T leukemogenesis.

Both Tcf/Lef transcription factors are expressed in developing T lymphocytes in the thymus and required for normal thymocyte survival and differentiation.

During normal thymocyte development, Notch3 is expressed at the transition between the CD4-CD8 double-negative and the CD4+CD8+double-positive stages; its expression drops markedly after this.